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KMID : 0361020230660010054
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Korean Journal of Otolaryngology - Head and Neck Surgery
2023 Volume.66 No. 1 p.54 ~ p.57
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Langerhans Cell Histiocytosis of the Tongue: A Clinical Case Report and Review of the Literature
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Kim Geun-Jeon
Shin Hyun-Il
Kim Sang-Yeon
Sun Dong-Il
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Abstract
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Langerhans cell histiocytosis (LCH) is commonly characterized by abnormal function anddifferentiation or proliferation of monocytes. In LCH, granulomatous lesions, including langerine-positive histocytes and inflammatory infiltrates, can occur at all tissues, particularly thebones, skin, lungs, and pituitary gland. Thirty nine-year-old male patient visited outpatientclinic with a mass on his tongue that had been presented one month prior. The initial size was2×1.5 cm, but it gradually grew larger. The authors performed an incisional biopsy under localanesthesia, and the pathological diagnosis confirmed that LCH of the tongue. Several studiesincluding bone marrow biopsy were performed to assess involvement of other organs.
These tests show that only the tongue was involved in this case. The patient underwent furthertreatment with low-dose radiotherapy. We present this case of tongue LCH with a review ofthe literature.
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KEYWORD
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Hematology, Langerhans cell histiocytosis, Tongue
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